Discovering molecular glues and PROTACs with biophysics and other assays
Watch our discussion on the expanding field of targeted protein degradation and the technologies used to characterize these unique molecules. In this emerging therapeutic modality, binders like molecular glues and proteolysis targeting chimera (PROTACs) induce proximity between intrinsic cellular degradation machinery and unwanted proteins of interest, leading to degradation of the target. This webcast includes a short introduction to the topic and a moderated panel discussion on trends and challenges in this exciting area of drug discovery.