Advancing mRNA purification: strategies for speed, consistency, and scalability

Purifying mRNA remains a persistent challenge for researchers developing vaccines and RNA-based therapeutics. Variability in yield, purity, and reproducibility can complicate process development and hinder scalability, particularly when handling long RNA transcripts. Advances in affinity-based purification and process design now offer promising solutions to these obstacles.

In this webinar, Peter Guterstam discusses key strategies for enhancing mRNA purification performance through innovations in poly(A)-tailed RNA capture and workflow optimization.

Topics covered:

• Common sources of variability and yield loss in mRNA purification workflows
• Strategies to optimize capture and elution of poly(A)-tailed RNA
• Methods to shorten purification cycles while maintaining product quality
• Approaches for building more scalable and reliable mRNA purification processes

Speaker:

Peter Guterstam, Ph.D.
Product Manager, Cytiva

For more information on Fibro dT adsorber, 0.4 mL, visit https://cytiva.link/gr4y4.
For more information on our mRNA manufacturing solutions, visit https://cytiva.link/n0xn3.