Abstract: The most widely used method to monitor Host Cell Protein (HCP) levels in biologics are ELISAs. ELISAs use specially designed polyclonal antibodie...

Abstract: Imaging systems are a ubiquitous part of gel and Western blotting workflows. Images generated by imaging systems enable you to determine the puri...

Abstract The most common method scientists use to monitor host cell protein (HCP) levels in biologics is the enzyme-linked immunosorbent assay (ELISA). Fo...

Host cell protein (HCP) is a significant class of process-related impurity that needs to be removed to adequately low levels during the manufacturing of bi...

Host cell proteins (HCP) are critical to quality control in biologics development. If left unremoved, they can cause immunogenic responses and reduce drug ...

Technical improvements related to cryogenic electron microscopy (cryo-EM) have triggered a revolution in structural biology and made single-particle cryo-E...

In the field of therapeutic mAbs, especially for those who mediate ADCC (Antibody Dependent Cellular Cytotoxicity), the attention is focus on their Fc-doma...

Most of the process-related impurities are critical quality attributes (CQAs) in biologics development and production. These include host cell proteins, DN...

Adenovirus associated virus (AAV) vectors are increasingly used for gene therapy. Manufacturing of safe and efficacious clinical-grade virus relies on scal...

The presentation covers the approach taken to develop and perform the SPR method used for Nucala product batch release identity and potency testing. The ke...